ABSTRACT
A full ODE model for the transmission of cholera is investigated, including both direct and indirect transmission and a nonlinear growth for pathogens. The direct problem is preliminarily studied and characterized in terms of reproduction number, endemic and disease free equilibria. The inverse problem is then discussed in view of parameter estimation and model identification via a Least Squares Approximation approach. The procedure is applied to real data coming from the recent Yemen cholera outbreak of 2017–2018.
Acknowledgements
This paper has been performed under the auspices of the G.N.F.M. of INdAM and partially supported by the Regione Campania Project ADVISE.
Disclosure statement
No potential conflict of interest was reported by the authors.