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Archives of Environmental Health: An International Journal Volume 19, 1969 - Issue 1
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Original Articles

Long-Term Exposure to Low Levels of Air Pollutants

Effects on Pulmonary Function in the Beagle

Thomas R. Vaughan Jr. MD US Department of Health, Education, and Welfare, Public Health Service, Consumer Protection and Environmental Health Service, National Air Pollution Control Administration, 1055 Laidlaw Ave, Cincinnati, 45237
,
Lesta F. Jennelle MS US Department of Health, Education, and Welfare, Public Health Service, Consumer Protection and Environmental Health Service, National Air Pollution Control Administration, 1055 Laidlaw Ave, Cincinnati, 45237
&
Trent R. Lewis PhD US Department of Health, Education, and Welfare, Public Health Service, Consumer Protection and Environmental Health Service, National Air Pollution Control Administration, 1055 Laidlaw Ave, Cincinnati, 45237
Pages 45-50 | Received 19 Nov 1968, Accepted 02 Dec 1968, Published online: 29 Apr 2013
 
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Abstract

One hundred and four beagles have been exposed for 18 months to natural and photochemically reacted auto exhaust, oxides of nitrogen and oxides of sulfur. No differences in singlebreath carbon monoxide diffusing capacity, dynamic pulmonary compliance, or total expiratory pulmonary resistance were found between exposed and control animals. Removal of reactive gases in the upper airway was studied during brief exposures in an additional small group of animals. Under these conditions, 100% removal of O3 and SO2, 90% removal of NO2, 73% removal of NO, and no removal of CO or hydrocarbon were found.

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EXPERIMENTAL STUDY OF THRESHOLD LIMIT OF NO2.
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