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Abstract
Mice exposed to a chronic dosage of 5.5 mg/kg/day of chlorophenothane (DDT) in their diets have been subjected to transplants of an experimental ependymoma. Compared to the controls, these animals show a decrease in the “take” of tumor transplant, and a significant increase in longevity. Autopsies on all animals revealed no evidence of liver tumors or other hepatic pathological findings. Possible mechanisms for an inhibitory effect of DDT on this experimental tumor are discussed.