The Serum Trypsin Inhibitor Capacity During Ozone Exposure

Abstract

Six young New Zealand rabbits were exposed to 0.4 ppm ozone for six hours a day, five days a week, for a calendar period of six months. Blood was drawn from the marginal vein of the ear at three-week intervals, and the trypsin inhibitor capacify (TIC) of the serum was determined and compared with the serum TIC values of six controls. Except for a sharp rise after the first day of exposure to ozone, the TIC values remained within normal limits. These results imply that long-term exposure to low concentrations of ozone does not destroy the serum antitrypsin factor.