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Abstract
Analysis of cadmium and zinc in the renal cortex of 67 Swedish subjects disclosed the same dependence on age as in US subjects. In the 6–50 year age group, cadmium content and the cadmium-zinc ratio were correlated to age; thereafter, there was a decrease in cadmium and zinc and in the cadmium-zinc ratios. The increase in zinc paralleled the increase in cadmium. The difference between total zinc and the amount of zinc equivalent to the amount of cadmium provides a measure of the physiological zinc content of the cortex; this fraction, 160 ppm (based on dry weight of renal cortex), did not vary with age. In the age groups over 60, cadmium content was significantly lower in women than in men.