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Abstract
This study evaluated the effect o f sulfuric acid aerosol exposure for 2 consecutive days on seven human biochemical blood parameters. A total of 20 human subjects were exposed to 100 μg/m3 (0.033 μM) sulfuric acid aerosol (0.5 μm mean mass diameter) for 4 hr/day for 2 consecutive days. A total of 17 human subjects wereexposed to 4 hr of ambient air on both exposure days. The chemical blood parameters were measured pre- and postexposure,and 20 hr after the second exposure: serum glutathione, red blood cell glutathione reductase, red blood cell glucose-6 -phosphate dehydrogenase, lysozyme, serum glutamic oxaloacetic acid transaminase, serum vitamin E, and 2, 3-diphosphoglycerate. The results indicate no significant response in any o f the seven biochemical blood parameters measured. At this level, repeated exposure did not over-burden the upper airway defenses against acid aerosol.