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Original Articles

Ethnic neutropenia and clozapine

Pages 342-345 | Received 26 Oct 2007, Published online: 06 Jul 2009
 

Abstract

Objectives: The aim of the present paper was to examine the concept of benign ethnic neutropenia and to consider the implications of ethnicity in the current clozapine regulatory system.

Method: The case of a young Palestinian man who lost access to clozapine due to a fall in his neutrophil count, is presented herein, and a brief review of ethnic variations in neutrophil levels is given.

Results: This patient's clozapine was ceased, with unfortunate consequences, despite his having normal immune function.

Conclusion: By using normative haematological data established in white populations, the Australian clozapine regulatory system places some non-white patients at a considerable disadvantage.

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