Relationship between Eye Dominance and Pattern Electroretinograms in Normal Human Subjects

Abstract

The authors conducted a study in 100 non-smoker healthy normal human subjects to find a relationship between eye dominance and macular function as tested by using transient stimulus and electroretinography. Eye preference procedure was carried out using two reference points and pattern electroretinograms (PERGs) were recorded using black and white checks, each check subtending 23'. Trace averager was retriggered every 300 milliseconds (ms) with data collection time of 150 ms. The difference in PERG P₅₀ amplitudes between right and left eyes was analyzed using Student's t test. There was no significant difference in PERG P₅₀ amplitudes between the right and left eye dominant subjects as well as no significant differences between the right and left eyes in right eye dominants and left eye dominants, but in the left-eye dominant group the left eye PERG P₅₀ amplitudes were significantly higher in females than males. Although pattern-reversal visual evoked potentials of healthy subjects provide electrophysiological evidence of lateralization in the nervous system, sensory eye dominance seems to have no correlation with macular function.

Keywords:

• eye preference
• lateralization
• macular function
• pattern electroretinography
• sensorimotor performance