Advanced search
Publication Cover
International Journal of Neuroscience Volume 118, 2008 - Issue 1
Submit an article Journal homepage
62
Views
1
CrossRef citations to date
0
Altmetric
Original

THE EFFECT OF PROGESTERONE ON TOTAL BRAIN TISSUE SIALIC ACID LEVELS IN EXPERIMENTAL EPILEPSY

SADRETTIN PENCE Department of Physiology, Faculty of Medicine University of Gaziantep, Gaziantep, Turkey
,
MEHMET BOSNAK Department of Physiology, Faculty of Medicine University of Gaziantep, Gaziantep, Turkey
,
NACIYE KURTUL Department of Chemistry, Faculty of Science Sutcu Imam University, Kahramanmaras, Turkey
,
METE GUROL UGUR Department of Obstetrics & Gynecology, Faculty of Medicine University of Gaziantep, Gaziantep, Turkey
,
IBRAHIM ERKUTLU Department of Neurosurgery, Faculty of Medicine University of Gaziantep, Gaziantep, Turkey
,
CAHIT BAGCI Department of Physiology, Faculty of Medicine University of Gaziantep, Gaziantep, Turkey
&
UNER TAN Department of Physiology, Medical School Cukurova University, Adana, Turkey
 show all
Pages 105-118 | Received 23 Jun 2006, Published online: 24 Aug 2009
 
Sample our Bioscience journals, sign in here to start your access, Latest two full volumes FREE to you for 14 days

Abstract

Epilepsy, the most common neurological disorder worldwide, changing cellular interactions and connectivity may have effects on sialic acid levels. A total of 80 mice were separated into 8 groups: the sham, control, pentylentetrazole (PTZ), PTZ plus progesterone, five dose progesterone, single dose progesterone, kindling, and kindling plus progesterone groups. Brains of each mice were extracted and were divided into five parts. The sialic acid levels were significantly different between the groups and also in the subgroups. The results suggested that progesterone may have an anti-seizure effect by decreasing sialic acid levels in mice. Further studies are needed to evaluate the role of progesterone on sialic acid levels and its role in the epilepsy pathogenesis.

Log in via your institution

Access through your institution

Log in to Taylor & Francis Online

Restore content access

Restore content access for purchases made as guest
Purchase options * Save for later

PDF download + Online access

  • 48 hours access to article PDF & online version
  • Article PDF can be downloaded
  • Article PDF can be printed
USD 65.00 Add to cart

Issue Purchase

  • 30 days online access to complete issue
  • Article PDFs can be downloaded
  • Article PDFs can be printed
USD 1,997.00 Add to cart

* Local tax will be added as applicable

Related Research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.