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International Journal of Neuroscience Volume 118, 2008 - Issue 3
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Effect of Pilopool on Forced Swimming Test in Mice

Hyun-Na Koo Department of Pharmacology, College of Oriental Medicine, Institute of Oriental Medicine, Kyung Hee University, Seoul, Republic of Korea
,
Jae-Young Um Department of Pharmacology, College of Oriental Medicine, Institute of Oriental Medicine, Kyung Hee University, Seoul, Republic of Korea
,
Hyung-Min Kim Department of Pharmacology, College of Oriental Medicine, Institute of Oriental Medicine, Kyung Hee University, Seoul, Republic of Korea
,
Eun-Hee Lee Division of Beauty Arts, Jeonbuk Science College, Jeongeup, Jeonbuk, Republic of Korea
,
Hyun-Jea Sung Graduate School of Alternative Medicine, Kyonggi University, Seoul, Republic of Korea
,
II-Kwang Kim Division of Bio-Nano Chemistry, Wonkwang University, Iksan, Jeonbuk, Republic of Korea
,
Hyun-Ja Jeong College of Pharmacy, VCRC of Wonkwang University, Iksan, Jeonbuk, Republic of Korea
&
Seung-Heon Hong College of Pharmacy, VCRC of Wonkwang University, Iksan, Jeonbuk, Republic of Korea
 show all
Pages 365-374 | Received 25 Jul 2007, Published online: 07 Jul 2009
 
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Abstract

Pilopool is composed of high molecular weight water-soluble chitosan, Allium sativum L. extract, mushroom extract, Dioscorea Batatas D., and purple bamboo salt. This study investigated the effect of Pilopool on performance of forced swimming test (FST). First, the immobility time was decreased in Pilopool-fed group in comparison with control group on FST. In blood serum, the contents of creatine kinase and lactic dehydrogenase were decreased and the contents of glucose and total protein were increased. The results predict a potential benefit of Pilopool as an anti-fatigue agent and for improving physical stamina.

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