Lymphomatosis cerebri with cauda equina lymphoma

Abstract

Purpose/aim

Lymphomatosis cerebri (LC) and cauda equina lymphoma are both rare forms of primary central nervous system lymphoma (PCNSL). LC is characterized by diffuse bilateral non-enhancing (or partially enhancing) inltrative lesions without mass effect, which can be easily confused with other forms of leukoencephalopathy and, thus, lead to delays in diagnosis.

Case report

For the first time, a case of LC concomitant with cauda equina involvement confirmed by brain stereotactic biopsy is presented.

Conclusions

This case highlights the necessity of using a multimodal strategy in diagnosing PCNSL, including multimodal magnetic resonance, cerebral spinal fluid cytology, flow cytometry and fluorodeoxyglucose positron emission tomography/computed tomography.

Keywords:

• primary central nervous system lymphoma
• lymphomatosis cerebri
• cauda equina
• CSF cytology
• flow cytometry

Disclosure statement

No potential conflict of interest was reported by the author(s).

Ethics statement

Written informed consent for the publication of this case report was obtained from the patient.

Author contributions

DT and JLL conceived and designed the study. RT analyzed the imaging data. GD prepared the figures and wrote the manuscript.