Kikuchi disease as a possible cause of ischaemic stroke: a case report

Abstract

Introduction

Kikuchi disease (KFD) is a rare and self-limiting benign disease which usually occurs in young women. The difference between our case and the previous case is that the initial symptom of this case is transient ischemic attack (TIA).

Methods

A 46-year-old female patient presented at the clinic with a 2-week history of paroxysmal left limb weakness and fever. Imaging examinations showed the multiple lymph nodes in neck enlarged bilaterally. Finally, we arranged a lymph node biopsy for the patient.

Results

The resulted of lymph node biopsy showed the disorder of lymph node structures, widespread histiocytic infiltration and cell nucleus fragments, suggesting KFD.

Conclusion

TIA as a complication of KFD has never been reported in the previous literature, which provided a new direction for diagnosis of TIA and suggested that KFD may be a rare cause of ischemic stroke.

Keywords:

• Transient ischaemic attack
• histiocyte necrotizing lymphadenitis
• Kikuchi-Fujimoto disease
• Kikuchi disease
• ischaemic stroke

Disclosure statement

No potential conflict of interest was reported by the author(s).

Additional information

Funding

This work was funded by National Natural Science Foundation of China grant funded by the China Government (grant number: 81400978) and the Natural Science Foundation of Hunan Province, China (grant number: 2018JJ2643).