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Review Article

Towards vaccine lifecycle management (VLM): A systematic literature review of the issues and challenges

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Received 29 Dec 2022, Accepted 29 Feb 2024, Published online: 22 Mar 2024
 

Abstract

The vaccine, a distinctive product with specific characteristics, plays a crucial role in enhancing human immunity against diseases for their eradication. Given the severe impact of the COVID-19 pandemic on humanity, numerous challenges lie ahead, underscoring the necessity to develop and enhance medical, economic, and managerial components of vaccine development, as well as to integrate digital technologies and coordinate all stakeholders to respond effectively to the epidemic. All of these considerations refer to the need for a vaccine lifecycle management approach. Despite existing literature, many studies focus on isolated stages, neglecting the essential holistic view required to understand interconnections and the overall impact of proposed solutions on the whole lifecycle. This study addresses this research gap, by systematically tackling major challenges throughout the vaccine lifecycle. Our research contributes to the literature by (a) providing a systematic examination of the literature surrounding Vaccine Lifecycle Management, offering insights into the existing challenges and issues faced in the various stages of vaccine development, production, distribution, and administration, and (b) proposing recommendations or directions for improvement in managing the entire lifecycle of vaccines. Our results could be valuable perspectives for decision-makers involved in the process.

Disclosure statement

No potential conflict of interest was reported by the authors.

Additional information

Notes on contributors

Allam Sanae

Sanae Allam, Ph.D. candidate at University Chouaib Doukkali – ENSA EL JADIDA, codirected with University Lyon 2 – INSA LYON, specialises in Industrial Engineering. Having obtained her diploma in Industrial Engineering from ENSA El Jadida in 2021, Sanae’s research focuses on the intricate domain of Vaccine Lifecycle Management (VLM). She explores the nexus of optimisation, supply chain management, product lifecycle management (PLM), and data management.

Sekhari Seklouli Aicha

Aicha Sekhari is a professor at University Lyon2 and a member of DISP laboratory, where she co-leads the ‘System Lifecycle Modeling and Optimization’ axis and heads the RTI Knowledge Transfer and Innovation Pole. Her research focuses on Product and Production Sustainability, including Product Lifecycle Management and Supply Chain Management. She advises PhD and Masters students in these fields. She previously served as the technical manager of EASYIMP FP7 FoF ICT NMPB project, developing an MBSE method for smart products. She is a member of the EcoSD research and industry association, contributing to Eco-PLM and Sustainable Product Development. Aicha coordinates several international research projects including FP7 ICT FI-PPP FITMAN and Erasmus Mundus programs. She also teaches Production Management, Quality Management Methods, and Norms for postgraduate and undergraduate degrees. Aicha received her Engineering Degree in Electronics in 1994 from the Algerian University of Engineering Science and her Ph.D. in Production Systems from the University of Joseph Fourier in Clermond Ferrand, France, in 2004.

El Bouzekri El Idrissi Adiba

Adiba El Bouzekri El Idrissi is a Professor at Chouaib Doukkali University specialising in Operational Research in Supply Chain, Data Management, Supply Chain Optimization, and Metaheuristics. She also teaches Production Management. She holds an authorisation to supervise research (HDR) in Industrial Engineering/Logistics from ENSA El Jadida and obtained her Doctorate in Operational Research in Logistics from the Faculty of Sciences and Techniques of Fes, focusing on Supply Chain Optimization, Data Management, and Metaheuristics.

El Kinani Noredine

Noredine El Kinani, Founder & CEO of Digital House Group in Vélizy-Villacoublay, France, also serves as the Operations Manager at CESAM SEED in the Paris region. Prior to his current roles, he worked as a consulting engineer at Altran Île-de-France and completed the Manager of Information Systems and Infrastructure, ‘PLM track,’ earning the title of Functional PLM Consultant at the PLM Academy.

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