Phosphatidylcholine-Cerebrosides Interactions: Influence of Cerebroside Acyl Chain Character

Abstract

We have measured the swelling properties, and force decay with bilayer separation, for single phase multi-lamellar arrays made from dioleoylphosphatidylcholine, and cerebrosides with primarily non-hydroxl acyl chains. The phase characteristics and interactive forces are found to be similar to bilayers made from DOPC and cerebrosides with primarily hydroxyl acyl chains. In all cases, cerebrosides are found to have little effect on the hydration and electrostatic forces.