Study on the analytical solution of the MSA for a one-component two-Yukawa potential in bovine serum albumin—NaC1 aqueous solution

Abstract

Using the mean spherical approximation (MSA), an explicit analytical equation of state (EOS) with non-dimensional variables for one-component two-Yukawa fluid is established based on the work of Blum, L., and Ubriaco, M., 2000, Molec. Phys., 98, 829. A simple and directly iterative method is found for obtaining an acceptable solution. The strict two-Yukawa EOS is used to correlate the experimental osmotic pressure data of aqueous bovine serum albumin (BSA)-NaCl solutions in the one-component assumption. Considering the experimental error, the correlation results are good, with only one regressed parameter (disperse energy parameter ∊). The deviation of correlation is discussed in detail. A concept of effective diameter, which obviously can decrease the deviation of correlation, is given.