![Sample our Environment & Agriculture journals, sign in here to start your access, latest two full volumes FREE to you for 14 days]({"type":"image" , "src" : "/sda/5934/TOC-Subject-Sample-2021-Environment-Agriculture.jpg"})
Abstract
Mycelia of Cunninghamella elegans were incubated in liquid Sabouraud medium containing 56 HM acridine. After 3 days, the culture medium was extracted with ethyl acetate and two metabolites were purified by high-performance liquid chromatography. Acridine trans- 1,2-dihydrodiol and 2-hydroxyacridine were identified by ultraviolet-visible absorption spectrophotometry, mass spectrometry, and proton nuclear magnetic resonance spectroscopy. The data support a proposed pathway in which acridine is oxidized to a transient arene oxide, which is then hydrated to form the dihydrodiol or rearranged to form the phenol.