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Physics and Chemistry of Liquids
An International Journal
Volume 53, 2015 - Issue 2
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Original Articles

Liposomal suspension of DSPC/cholesterol with polyethylene glycol: a study by light and X-ray scattering

Aboozar NasrollahiDepartment of Physics, University of Sistan and Baluchestan, Zahedan98135-674, Iran
,
Soheil SharifiDepartment of Physics, Faculty of Sciences, Ferdowsi University of Mashhad, Mashhad91775-1436, IranCorrespondence[email protected]
&
Dawood BarahoieDepartment of Physics, University of Sistan and Baluchestan, Zahedan98135-674, Iran
Pages 221-229 | Received 16 Feb 2014, Accepted 18 Aug 2014, Published online: 14 Oct 2014
 
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Abstract

To study the structure and dynamic properties of liposomal suspension with polyethylene glycol (PEG), we used small-angle X-ray scattering (SAXS) and dynamic light scattering techniques. Light scattering experiment revealed that increase in PEG concentration decreased diffusion coefficient of liposomal structure. Moreover, cholesterol addition contributed to reduction of collective diffusion coefficient in the presence of PEG polymer. The SAXS experiment showed that the size and interaction of the liposome nanoparticle increased with an increase in PEG and cholesterol concentration.

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