Solubility and thermodynamic properties of acetaminophen in 1-hexyl-4-methylpyridinium bromide and water mixtures

ABSTRACT

The solubility data of acetaminophen in binary mixtures of 1-hexyl-4-methylpyridinium bromide and water were obtained over the temperature range from 293.15 to 313.15 K by using the gravimetric method under atmospheric pressure. Using the experimentally measured solubility values, the thermodynamic properties of dissolution, mixing and transfer processes were evaluated. The measured solubilities were correlated by the modified Wilson and the electrolyte non-random two liquid (E-NRTL) models.

KEYWORDS:

• Acetaminophen
• solubility
• ionic liquid
• activity coefficient model

Disclosure statement

No potential conflict of interest was reported by the authors.

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