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Articles

Determination of Abraham model solute descriptors for o-acetoacetanisidide based on experimental solubility data in organic mono-solvents

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Pages 528-535 | Received 28 Jun 2018, Accepted 01 Jul 2018, Published online: 11 Jul 2018
 

ABSTRACT

Spectrophotometric methods were used to measure the mole fraction solubility of o-acetoacetanisidide dissolved in 13 alcohol solvents (ethanol, 1-propanol, 1-butanol, 1-pentanol, 1-hexanol, 1-heptanol, 2-propanol, 2-butanol, 2-methyl-1-propanol, 2-methyl-2-propanol, 2-methyl-2-butanol, 3-methyl-1-butanol and 4-methyl-2-pentanol), in 3 dialkyl ether solvents (diisopropyl ether, dibutyl ether and methyl tert-butyl ether), in 6 alkyl alkanoate solvents (methyl acetate, ethyl acetate, propyl acetate, butyl acetate, pentyl acetate and methyl butyrate) and in 1 alkanenitrile solvent (propanenitrile) at 298.15 K. Solute descriptors were calculated for o-acetoacetanisidide by analysing the measured solubility data in accordance with the Abraham solvation parameter model. The calculated solute descriptors describe the observed solubility data to within 0.099 log units.

Acknowledgments

Melanie Che, Avi Gupta, Reese Neal, Ellen Qian and David Yue thank the University of North Texas’s Texas Academy of Math and Science (TAMS) programme for a summer research award.

Samantha Downs, Tiffany Mayes and Olivia Rose thank the US Department of Education for support provided to them under the Upward Bound Math and Science Programme.

Disclosure statement

No potential conflict of interest was reported by the authors.

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