ABSTRACT
Experimental solubilities have been determined for xanthone dissolved in 15 different alcohol solvents (ethanol, 1-propanol, 1-butanol, 1-pentanol, 1-hexanol, 1-heptanol, 1-octanol, 2-methyl-1-propanol, 3-methyl-1-butanol, 2-ethyl-1-hexanol, 2-propanol, 2-butanol, 4-methyl-2-pentanol, 2-methyl-2-propanol and 2-methyl-2-butanol), in five alkyl acetate solvents (methyl acetate, ethyl acetate, propyl acetate, butyl acetate and pentyl acetate), in diisopropyl ether and in 2-ethoxyethanol at 298.2 K. In total, solubility measurements were performed in 22 organic solvents of varying polarity and hydrogen-bonding character. Results of the experimental measurements were used to calculate the Abraham model solute descriptors for xanthone. The calculated solute descriptors describe the experimental solubility data to within 0.096 log units.
Acknowledgments
Melanie Che, Avi Gupta, Reese Neal, Ellen Qian and David Yue thank the University of North Texas’s Texas Academy of Math and Science (TAMS) programme for a summer research award.
Disclosure statement
No potential conflict of interest was reported by the authors.