112
Views
3
CrossRef citations to date
0
Altmetric
Clinical features - Original Research

Impact of serum magnesium levels at hospital discharge and one-year mortality

ORCID Icon, , , ORCID Icon, ORCID Icon, , , , & ORCID Icon show all
Pages 47-51 | Received 09 Mar 2021, Accepted 13 May 2021, Published online: 31 May 2021
 

ABSTRACT

Background

We aimed to determine the optimal range of discharge serum magnesium in hospitalized patients by evaluating one-year mortality risk according to discharge serum magnesium.

Methods

This was a single-center cohort study of hospitalized adult patients who survived until hospital discharge. We classified discharge serum magnesium, defined as the last serum magnesium within 48 hours of hospital discharge, into ≤1.6, 1.7–1.8, 1.9–2.0, 2.1–2.2, and ≥2.3 mg/dL. We assessed one-year mortality risk after hospital discharge based on discharge serum magnesium, using discharge magnesium of 2.1–2.2 mg/dL as the reference group.

Results

Of 39,193 eligible patients, 8%, 23%, 34%, 23%, and 12% had a serum magnesium of ≤1.6, 1.7–1.8, 1.9–2.0, 2.1–2.2, and ≥2.3 mg/dL, respectively, at hospital discharge. After the adjustment for several confounders, discharge serum magnesium of ≤1.6, 1.7–1.8, and ≥2.3 mg/dL were associated with higher one-year mortality with hazard ratio of 1.35 (95% CI 1.21–1.50), 1.14 (95% CI 1.06–1.24), and 1.17 (95% CI 1.07–1.28), respectively, compared to discharge serum magnesium of 2.1–2.2 mg/dL. There was no significant difference in one-year mortality between patients with discharge serum magnesium of 1.9–2.0 and 2.1–2.2 mg/dL.

Conclusion

The optimal range of serum magnesium at discharge was 1.9–2.2 mg/dL. Both hypomagnesemia and hypermagnesemia at discharge were associated with higher one-year mortality.

Acknowledgments

None stated.

Declaration of funding

This research received no specific grant from any funding agency in the public, commercial, or not-for-profit sectors.

Declaration of financial/other relationships

None to declare.

Log in via your institution

Log in to Taylor & Francis Online

PDF download + Online access

  • 48 hours access to article PDF & online version
  • Article PDF can be downloaded
  • Article PDF can be printed
USD 65.00 Add to cart

Issue Purchase

  • 30 days online access to complete issue
  • Article PDFs can be downloaded
  • Article PDFs can be printed
USD 708.00 Add to cart

* Local tax will be added as applicable

Related Research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.