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Original Article

Mechanical versus chemical keratolysis by dermatophytes

Pages 87-90 | Published online: 09 Jul 2009
 

Abstract

It is suggested that the concept of enzymatic keratolysis by dermatophytes stands in need of revision.

Non-keratin containing aqueous extracts from human hair and nails have been shown capable of supporting the growth of the pseudoparasitic phase of certain dermatophytes.

Destruction of such structures as hair and nails by an infecting fungus may be due to mechanical disintegration following invasion of the non-fibrillary matrix; the fungus feeding on the non-keratins without need to digest the keratin molecule.

Résumé

L'auteur suggère que soit révisée l'idée que l'on se fait actuellement de la lyse enzymatique de la kératine par les dermatophytes.

Des extraits aqueux de cheveux et d'ongles humains, exempts de kératine, permettent la croissance de la phase pseudo-parasitaire de certains dermatophytes.

La destruction de l'ensemble complexe qu'est un cheveu ou un ongle par un champignon parasite peut être due à une désintégration mécanique faisant suite à l'envahissement de la matrice non fibrillaire; la nutrition du champignon se faisant aux dépens de matériel étranger à la kératine, ne nécessite pas la lyse de la molécule de ce composé.

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