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Original Article

Studies on the genus Basidiobolus with reclassification of the species pathogenic for man

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Pages 231-241 | Published online: 09 Jul 2009
 

Abstract

The etiologic agent of human subcutaneous phycomycosis was found to be a species of Basidiobolus which is characterized by the lack of a distinctive odor, by being able to grow well at human body temperature and in having smooth-walled zygospores. These features separate it from the saprophyte, B. ranarum, which has a distinctive odor, does not grow well at 37°C. and has rough-walled zygospores. It is separated from B. haptosporus on the basis that this saprophyte is not well-adapted for growth at human body temperature. B. magnus and B. microsporus possess other distinctly differing morphological features. The pattern is considered by the authors to be of the same species as B. meristosporus, a thermotolerant fungus which does not differ significantly in morphology from the human pathogen.

Resume

L'agent étiologique de la phycomycose sous-cutanée chez l'homme a été identifié à une espèce du genre Basidiobolus dépourvue d'odeur distinctive, cultivable à 37°C., présentant des zygospores à paroi cellulaire lisse. Ces caractères doivent le faire différencier du saprophyte B. ranarum qui a une odeur distinctive, ne peut être cultivé facilementà 37°C. et possède des zygospores à paroi cellulaire rugueuse. On doit le distinguer de B. haptosporus, ce dernier étant un saprophyte difficilement cultivable à 37°C. Par ailleurs, B. magnus et B. microsporus ont des caractères morphologiques nettement différents. La souche pathogène est considérée par les auteurs comme étant identifiable à l'espèce B. meristosporus, champignon qui, pour sa croissance, tolère des variations de température et qui, morphologiquement, ne diffère pas du pathogène humain de façon significative.

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