Abstract
Pregnant sheep inoculated with Aspergillus fumigatus conidia developed agglutinating and precipitating antibodies for mycelial antigens. The agglutinins were initially exclusively of the IgM class, but were later supplemented by IgG antibodies, although IgM production was usually sustained throughout the serological response. Precipitins active in the immunodiffusion test were of the IgG class. They developed later in the immune response than agglutinins and declined more rapidly. The precipitins and IgG agglutinins were more closely associated with recent active infection than IgM agglutinins.
Résumé
Des brebis gravides inoculées par voie intraveineuse avec des conidies d'Aspergillus fumigatus ont développé des anticorps agglutinants contre les antigènes mycéliens.
On montre que les agglutinines sont des IgM et IgG mais les anticorps qui donnent la réaction d'immunodiffusion en gel sont seulement de la classe IgG. Enfin, les anticorps de la classe des IgG se sont associés plus exactement avec l'infection récente que ceux la classe IgM.