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Original Article

Distribution of the two mating types among Histoplasma capsulatum isolates obtained from an urban histoplasmosis outbreak

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Pages 155-157 | Accepted 24 Jul 1983, Published online: 09 Jul 2009
 

Abstract

The mating type distribution among the 28 Histoplasma capsulatum isolates obtained from the histoplasmosis outbreaks which occurred in Indianapolis in 1978–1979 and 1980–1981 was studied. The overall ratio of + and — types was 1:2·5. The isolates from disseminated patients showed a 1(+):1(-) ratio while the isolates from non-disseminated pulmonary cases showed a 1(+):4(-) ratio. The frequency of the + type in these outbreaks was three times higher than that of the previous study. This was due to an unusually high prevalence of the + type among the patients with disseminated histoplasmosis.

RESUME

Les auteurs étudient la distribution du signe sexuel de 28 souches obtenues lors de l'épidémie d'histoplasmose survenue à Indianapolis en 1978–79 et en 1980–81. Le rapport total des types + et - est 1:25. Les souches isolées de cas de maladie disséminée sont dans le rapport 1(+):1(-) tandis que les souches provenant de cas pulmonaires non disséminés sont dans le rapport 1(+):4(-). Dans ces épidémies, la fréquence du type + est 3 fois plus haute que lors d'une étude précédente. Ceci est dû à une incidence anormalement haute du type + parmi les malades atteints d'histoplasmose disséminée.

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