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Original Article

Immunodiffusion studies on the antigens of Histoplasma capsulatum: comparison of mycelial histoplasmin with the yeast phase reagent Histolyn-CYL®

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Pages 487-491 | Accepted 20 Jun 1984, Published online: 09 Jul 2009
 

Abstract

Immunodiffusion assays were performed to determine if H and M antigens associated with mycelial histoplasmin were present in the yeast phase reagent, Histolyn-CYL® (H-CYL). Neither H nor M antigens could be detected in H-CYL. However, when H-CYL was reacted against human histoplasmal sera a positive reaction was evidenced in all instances in which a response was elicited with a reference mycelial immunodiffusion reagent.

Riassunto

Sono state eseguite prove di immunodiffusione per accertare se nel reattivo in fase lievito Histolyn-CYL®(H-CYL) erano presenti antigeni H ed M associati all'istoplasmina miceliale. Questi antigeni non sono stati rinvenuti. Tuttavia, quando H-CYL veniva fatto reagire contro un siero umano anti-istoplasma, si evidenziava una reazione positiva tutte le volte che veniva indotta una risposta con un reattivo miceliale di riferimento per immunodiffusione.

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