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Original Article

Risk stratification of prostate cancer 2016

Pages S54-S59 | Accepted 09 Mar 2016, Published online: 17 Aug 2016
 

Abstract

Prostate cancer is a common malignancy in men, but its management is fraught with controversy owing to its variable biologic and clinical behavior. Despite evidence that PSA screening reduces prostate cancer specific metastasis and death, it has not gained acceptance by various health authorities. Nevertheless, recent advances in biomarker development potentially address many of the shortcomings of routine PSA testing alone, including improved specificity for the detection of clinically significant cancer, optimized risk stratification to aid clinical management decisions, and discovery of genetic variants that may guide optimized therapy of advanced disease.

Disclosure statement

The author reports no conflicts of interest. The author alone is responsible for the content and writing of the paper.

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