Urinary Excretion of Aminoacetone following Administration of L-Threonine in Man

Abstract

A glucose diet and complete starvation resulted in a 30–40 per cent decrease of the urinary aminoacetone in man, whereas the excretion of δ-amino-levulinic acid remained unchanged. Oral and parenteral administration of L-threonine significantly enhanced the urinary excretion of aminoacetone. Threonine loading also produced a slight increase in the excretion of glycine, but no change in the excretion of δ-aminolevulinic acid.

Key Words:

• Amino acids
• glycine
• ketone bodies
• threonine