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Scandinavian Journal of Clinical and Laboratory Investigation Volume 53, 1993 - Issue 3
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Original

Van Beaumont's formula is valid during haemodialysis. Spectrophotometric determination of body circulating haemoglobin

K. C. Rasmussen Department of Nephrology, Herlev Hospital, University of Copenhagen, Denmark
,
R. Hansen Department of Nephrology, Herlev Hospital, University of Copenhagen, Denmark
,
S. Fugleberg Department of Nephrology, Herlev Hospital, University of Copenhagen, Denmark
&
N. Fogh-Andersen Department of Clinical Chemistry, Herlev Hospital, University of Copenhagen, Denmark
Pages 211-214 | Received 01 Nov 1991, Accepted 01 Jul 1992, Published online: 29 Mar 2011
 
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Abstract

Van Beaumont's formula is a convenient method to calculate changes in plasma volume from changes in haematocrit. The calculation is based on the assumption of a constant body red-cell volume. In order to evaluate the validity of this assumption during isovolaemic haemodialysis, we measured body circulating haemoglobin, blood volume and plasma volume by carbon monoxide dilution. No change in body circulating haemoglobin or plasma volume occurred by either method. Therefore, we conclude that van Beaumont's formula is valid during isovolaemic haemodialysis.

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