The Transmucosal Electrical Potential Difference across the Human Rectum in Vivo Following Perfusion of Different Electrolyte Solutions

Abstract

Dalmark, M. 1970. The Transmucosal Electrical Potential Difference across the Human Rectum in Vivo Following Perfusion of Different Electrolyte Solutions. Scand. J. Gastroent. 5, 421-426.

Experiments have been carried out to investigate whether the transmucosal electrical potential difference (PD) across the human rectum in vivo was affected by alterations of ionic composition of the luminal solution. Only small changes of the PD were observed during perfusion with different concentrations of potassium, calcium, and chloride. There was a small decrease in the PD following a decrease in the sodium ion concentration, and a rise in the PD following substitution of chloride with equivalent amounts of sulphate.

Key-words:

• Biological transport
• elcctrophysiology
• intestinal mucosa
• membrane potentials
• rectum