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Scandinavian Journal of Infectious Diseases Volume 39, 2007 - Issue 2
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SHORT COMMUNICATION

Contribution of procalcitonin to occult bacteraemia detection in children

Christele Gras-Le Guen From the Paediatric Intensive Care Unit, CHU, Nantes, France; UPRES EA, School of Medicine, Nantes, FranceCorrespondence[email protected]
,
Caroline Delmas From the Paediatric Intensive Care Unit, CHU, Nantes, France
,
Elise Launay From the Paediatric Intensive Care Unit, CHU, Nantes, France
,
Jocelyne Caillon UPRES EA, School of Medicine, Nantes, France; Laboratory of Bacteriology, CHU, Nantes, France
,
Virginie Loubersac Laboratory of Biochemistry, CHU, Nantes, France
,
Georges Picherot Pediatric Emergency Department, CHU, Nantes, France
&
J. Christophe Roze From the Paediatric Intensive Care Unit, CHU, Nantes, France
 show all
Pages 157-159 | Received 15 Mar 2006, Published online: 08 Jul 2009
 
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Abstract

We conducted a prospective study in 215 children, 3 to 36 months of age, presenting with fever ≥39°C without obvious origin, in order to evaluate the diagnostic value of procalcitonin (PCT) in detection of occult bacteraemia. PCT associated with white blood cell count constitutes an efficient screening method with sensitivity 100%, specificity 61.9% and positive and negative likelihoods ratios of 2.62 and 0, respectively

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