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Scandinavian Journal of Infectious Diseases Volume 39, 2007 - Issue 4
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ORIGINAL ARTICLE

Infective endocarditis due to community-associated methicillin-resistant Staphylococcus aureus in injection drug users may be associated with Panton-Valentine leukocidin-negative strains

Constantine Tsigrelis From the Department of Medicine, Mayo Clinic College of Medicine, Rochester, MN, USA; Divisions of Infectious Diseases, Mayo Clinic College of Medicine, Rochester, MN, USACorrespondence[email protected]
,
Matthew D. Armstrong From the Department of Medicine, Mayo Clinic College of Medicine, Rochester, MN, USA
,
Nicholas E. Vlahakis From the Department of Medicine, Mayo Clinic College of Medicine, Rochester, MN, USA; Pulmonary and Critical Care Medicine, Mayo Clinic College of Medicine, Rochester, MN, USA
,
John A. Batsis From the Department of Medicine, Mayo Clinic College of Medicine, Rochester, MN, USA; Primary Care Internal Medicine, Mayo Clinic College of Medicine, Rochester, MN, USA
&
Larry M. Baddour From the Department of Medicine, Mayo Clinic College of Medicine, Rochester, MN, USA; Divisions of Infectious Diseases, Mayo Clinic College of Medicine, Rochester, MN, USA
Pages 299-302 | Received 06 Sep 2006, Published online: 08 Jul 2009
 
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Abstract

Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) isolates that cause infective endocarditis in injection drug users (IDUs) are distinct from CA-MRSA strains that cause endocardial infection as a complication of skin and soft tissue infections. We present a case of CA-MRSA infective endocarditis, review pertinent cases previously published, and describe the molecular characteristics of strains from IDUs and patients with skin and soft tissue infections.

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