Resonance Rayleigh scattering and resonance nonlinear scattering of the palladium(II)–acetazolamide chelate with eosin Y and their analytical application

ABSTRACT

A simple, rapid, and convenient method based on ion association for the determination of acetazolamide has been developed. Acetazolamide can react with palladium(II) to form cationic chelate at sodium acetate–acetic acid buffer solution, which can further react with eosin Y to form an ion association complex. As a result, the resonance Rayleigh scattering, second-order scattering, and frequency doubling scattering intensities are enhanced. Analytical wavelengths of resonance Rayleigh scattering, second-order scattering, and frequency doubling scattering located at 298, 558, and 338 nm, and the linearity range are 0.014–2.5, 0.034–2.5, and 0.119–2.4 µg mL⁻¹ respectively. In addition, the optimum conditions and the effect of coexisting substances are investigated. Besides, the structure of ion association complex, the reaction mechanism and the reasons for the enhancement of scattering are discussed through infrared spectra, absorption spectra, and quantum chemical calculations.

KEYWORDS:

• Acetazolamide
• eosin Y
• palladium(II)
• resonance nonlinear scattering
• resonance Rayleigh scattering

Additional information

Funding

Great thanks for the support from the Research Project of Health and Family Planning Commission of Shanxi Province (No. 201602025), Technology Start Funding Project (popular item) in Changzhi Medical College (No. QDZ201515). Changzhi Medical College Training Programs of Innovation and Entrepreneurship for Undergraduates (No. D2016017).