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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 35, 2005 - Issue 17
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Original Articles

Sodium Borohydride–Solid LiClO4: An Effective Reagent for Reducing Aldehydes and Ketones in Aprotic Solvent

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Pages 2271-2276 | Received 16 Dec 2004, Published online: 18 Aug 2006
 

Abstract

An efficient and simple method for the reduction of aldehydes, ketones and acid chlorides has been accomplished by using NaBH4–solid LiClO4 in mild conditions at ambient temperature with complete chemoselectivity in reduction of α,β‐unsaturated aldehydes and ketones. The reaction is fast with high yield and simple workup.

Acknowledgments

We are grateful to the research council of Sharif University for financial support.

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