Abstract
The synthesis of new 1,2,4‐ and 1,3,4‐oxadiazole derivatives as potential nonpeptide angiotensin II receptor antagonists is described. The quinoxalinone systems used as the “northern moiety” in these compounds were alkylated through a liquid/liquid phase‐transfer catalysis protocol, with good yields and high nitrogen‐ to oxygen‐alkylated product (N/O) ratios.
Keywords:
Acknowledgments
The authors are indebted to CNPq and FUNCAP for financial support of this work.