Thermal and Microwave‐Assisted Conjugate Additions of Indole on Electron‐Deficient Nitro‐olefins

Abstract

Conjugate addition of indole on nitro‐olefins was carried out by three different methods: (i) thermal heating in a sealed tube, (ii) reaction with indolyl magnesium iodide, and (iii) microwave irradiation. Comparison of the results indicated that the microwave technique is most efficient.

Keywords:

• Conjugate additions
• indole
• microwave
• nitro‐olefins

Acknowledgments

We are grateful to A. P. Gadgil for IR spectra, J. P. Chaudhari for NMR spectra, and V. S. Shinde and D. S. Shishupal for mass spectra.