Abstract
A convenient and efficient method for the synthesis of 1,5‐benzodiazepines by the reaction of o‐phenylenediamines (OPDA) and ketones with hydrogens at the α‐position has been developed. The reaction is carried out at room in the presence of a catalytic amount of magnesium perchlorate under solvent‐free conditions.
Acknowledgment
The authors thank the Science Research Foundation of Hebei Normal University and National Natural Science Foundation of China (20477009) for financial support of this work.