Reductive Deoximation of Aryloximes into Hydrocarbons by Hydrazine/KOH: A Novel Application of the Wolff–Kishner Reduction

Abstract

We report the reductive deoximation of different substituted aryl, diaryl, and aralkyloximes into the respective methyl or methylene derivatives by hydrazine hydrate/KOH at reflux in satisfactory yields.

Keywords:

• Aryloximes
• deoximation
• hydrocarbons
• hydrazine hydrate
• Wolff–Kishner reduction

Acknowledgment

H. M. Nanjundaswamy thanks the joint director of Public Health Institute and the commissioner of H & F W Services, Bangalore, India, for encouragement and SIF, Indian Institute of Science, Bangalore, India for providing the NMR facility.