Iodine‐Mediated Synthesis of 2‐Arylbenzoxazoles, 2‐Arylbenzimidazoles, and 1,3,5‐Trisubstituted Pyrazoles

Abstract

2‐Arylbenzoxazoles and 2‐arylbenzimidazoles were synthesized by the reaction of aldehydes with 2‐aminophenol and O‐phenylenediamines in the presence of iodine. 1,3,5‐Trisubstituted pyrazoles were synthesized from chalcones and hydrazines in the presence of iodine.

CDRI Communication No. 6509.

Keywords:

• Benzimidazoles
• benzoxazoles
• iodine
• oxidative aromatization
• single pot
• 1,3,5‐trisubstituted pyrazoles

Acknowledgment

We are thankful to Sophisticated Instrumentation Analytical Facility, Central Drug Research Institute (SAIF, CDRI) Lucknow, for providing spectroscopic data.

Notes

CDRI Communication No. 6509.