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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 36, 2006 - Issue 15
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Original Articles

Convergent One‐Pot Synthesis of 3‐Substituted Quinazolin‐4(3H)‐ones under Solvent‐Free Conditions

Kurosh Rad‐Moghadam Department of Chemistry, Guilan University, Rasht, IranCorrespondence[email protected]
,
Manoochehr Mamghani Department of Chemistry, Guilan University, Rasht, Iran
&
Laleh Samavi Department of Chemistry, Guilan University, Rasht, Iran
Pages 2245-2252 | Received 07 Oct 2005, Published online: 16 Feb 2007
 
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Abstract

A convenient method for the synthesis of 3‐substituted quinazolin‐4(3H)‐ones using the convergent reactions of formic acid, a primary amine, and isatoic anhydride under solvent‐free conditions and with brief microwave irradiation is described.

Acknowledgment

We gratefully acknowledge financial support from the Research Council of Guilan University.

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