Clay‐Mediated Selective Hydrolysis of 5′‐O‐Acetyl‐2′,3′‐isopropylidene/Cyclohexylidene Nucleosides

Abstract

A generalized procedure for the selective hydrolysis of 5′‐O‐acetyl‐2′,3′‐isopropylidene/cyclohexylidene nucleosides with a solid catalyst, Montmorillonite K‐10 in refluxing methanol, to furnish 5′‐O‐acetyl‐nucleosides is described.

Keywords:

• Montmorillonite K 10
• isopropylidene‐nucleoside hydrolysis
• 5‐O‐acetyl‐nucleosides

Acknowledgment

D. M. thanks CSIR (Delhi) for its financial assistance during this work.