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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 36, 2006 - Issue 16
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Original Articles

Solid‐State Synthesis of 4‐[(Indol‐3‐yl)‐arylmethyl]‐1‐phenyl‐3‐methyl‐5‐pyrazolones by Catalysis of Molecular Iodine

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Pages 2389-2399 | Received 10 Jan 2006, Published online: 22 Sep 2006
 

Abstract

4‐[(Indol‐3‐yl)‐arylmethyl]‐1‐phenyl‐3‐methyl‐5‐pyrazolones could be smoothly and effectively obtained in good yields through the iodine‐catalyzed reactions under solid‐state conditions at room tempertaure. The three‐component approach in a one‐pot procedure was reported for the first time. A possible mechanism was suggested to elucidate the remarkable reaction selectivities.

Acknowledgment

We are grateful for the financial support from the Nature Science Foundation of China (project number 20402013).

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