New Method of Synthesizing N‐Alkoxycarbonyl‐N‐arylamide with Triphosgene

Abstract

N‐Chloroformyl‐N‐arylcarbamate, the key intermediate for the synthesis of some excellent pesticides, was synthesized through a new method with triphosgene instead of toxic phosgene. It cannot be obtained through the traditional method using triethylamine as a nucleophile. When triethylamine was replaced by a stronger base, sodium hydride, the product was obtained in good yield.

Keywords:

• Chlorocarbonylation
• N‐chloroformyl‐N‐arylcarbamate
• triphosgene

Acknowledgments

This study was supported by the Doctor Foundation of Liaoning Province, China (No. 20031068).