Unexpected Formation of Bicyclic Cyclopropane Lactam and Pyridone from the Reaction of cis‐2‐Aryl‐1‐carbomethoxy‐3,3‐dicynocyclopropane with Primary Aliphatic Amine via Isomerization and Rearrangement

Abstract

The novel process for preparation of fused bicyclic cyclopropane lactams and multisubstituted pyridones was described. It is the first example of a successful isomerization and rearrangement of the cis‐cyclopropane with primary aliphatic amine.

Keywords:

• Cyclopropane lactam
• isomerization
• primary aliphatic amine
• pyridone
• rearrangement

Acknowledgment

Thanks are due to the National Natural Science Foundation of China for financial support (No. 20472047).