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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 36, 2006 - Issue 22
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Original Articles

4,5‐Dihydrothiazoline—A New Protecting and Activating Group for Generation of α‐Aminocarbanions of Secondary Amines

Kamal Nain Singh Department of Chemistry, Panjab University, Chandigarh, IndiaCorrespondence[email protected]
,
Paramjit Singh Department of Chemistry, Panjab University, Chandigarh, India
&
Amarjit Kaur Department of Chemistry, Panjab University, Chandigarh, India
Pages 3339-3343 | Received 27 Apr 2006, Published online: 23 Nov 2006
 
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Abstract

4,5‐Dihydrothiazoline has been successfully used as a protecting and activating group for synthesis of various 1‐substituted 1,2,3,4‐tetrahydroisoquinolines via a lithiation–electrophillic substitution reaction sequence.

Acknowledgment

Financial support from CSIR, New Delhi, India, is gratefully acknowledged.

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