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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 36, 2006 - Issue 23
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Original Articles

Synthesis of New Quinoline Derivatives

Judit Tóth Research Group of the Hungarian Academy of Sciences, Department of Organic Chemical Technology, Technical University of Budapest, Budapest, Hungary
,
Gábor Blaskó EGIS Pharmaceuticals Ltd., Budapest, Hungary
,
András Dancsó EGIS Pharmaceuticals Ltd., Budapest, Hungary
,
László Tőke Research Group of the Hungarian Academy of Sciences, Department of Organic Chemical Technology, Technical University of Budapest, Budapest, Hungary
&
Miklós Nyerges Research Group of the Hungarian Academy of Sciences, Department of Organic Chemical Technology, Technical University of Budapest, Budapest, HungaryCorrespondence[email protected]
Pages 3581-3589 | Received 02 May 2006, Published online: 24 Nov 2006
 
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Abstract

The synthesis of some new functionalized quinolyl derivatives has been described, based on the 1,3‐dipolar cycloaddition of an azomethine ylide, generated from sarcosine or N‐benzylglycine and paraformaldehyde, to 2‐chloro‐3‐quinolinecarbaldehydes.

Acknowledgments

This work was financially supported by the National Fund for Science and Research, Hungary (OTKA Project No. T 046196). N. M. thanks the Hungarian Academy of Sciences for a Bolyai J. Fellowship. A grant from the József Varga Foundation provided to J. T. is gratefully appreciated.

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