Convenient Synthesis of Benzene‐1,3,5‐tricarbaldehyde and Congeners

Abstract

A convenient synthesis of benzene‐1,3,5‐tricarbaldehyde was developed as well as benzaldehyde derivatives carrying one or two latent aldehyde groups. The asymmetric derivatives may serve as versatile scaffolds for the synthesis of sectorial dendrimers and multifunctional molecules.

Keywords:

• aldehydes
• diols
• lithiation
• oxidations
• reductions

Acknowledgments

The authors thank the Swedish Science Council, the Royal Physiographic Society in Lund, and the Lund, University Research School of Medicinal Sciences for financial support.