Radical Cyclization Route to the Stereoselective Synthesis of (+)‐trans‐Cognac Lactone and (+)‐trans‐Aerangis Lactone

Abstract

Stereoselective total synthesis of two chiral lactones, (+)‐trans‐cognac lactone (1b) and (+)‐trans‐aerangis lactone (2c), has been achieved from the same intermediate using a radical‐based cyclization route.

Keywords:

• aerangis lactone
• chiral lactones
• cognac lactone
• natural products

Acknowledgment

M. B. thanks the Council for Scientific and Industrial Research (CSIR), New Delhi, for the award of a fellowship.

Notes

IICT Communication No. 060310