Direct Synthesis of Aromatic Nitriles from Aldehydes Using Hydroxylamine and Oxalyl Chloride

Abstract

Various aromatic and heterocyclic nitriles were prepared in good to high yields in a direct one‐pot process by heating the corresponding aldehydes with hydroxylamine and oxalyl chloride as reagents.

Keywords:

• aldehydes
• hydroxylamine hydrochloride
• nitriles
• oxalyl chloride
• triethylamine

Acknowledgments

We thank the K. N. Toosi University of Technology Research Council and Kermanshah Oil Refining Company for financial support.