Triflouroacetic Acid as an Efficient Catalyst for the Synthesis of Quinoline

Abstract

Triflouroacetic acid efficiently catalyzed the Friedländer synthesis of quinolines through a condensation reaction of an 2‐aminoaryl ketone with an activated α‐CH acid such as cyclic or acyclic β‐dicarbonyl or cyclic ketone compounds under solvent‐free conditions with high yields within several minutes.

Keywords:

• Friedländer annulation
• quinolines
• triflouroacetic acid

Acknowledgment

We gratefully acknowledge the financial support from the Research Council of Shahid Beheshti University.